A flavanone and antimicrobial activities of the constituents of extracts from Mundulea sericea

Journal article

Authors/Editors

Mazimba, Ofentse

Research Areas

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Publication Details

Author list: Mazimba O, Masesane IB, Majinda RRT

Publisher: Taylor & Francis: STM, Behavioural Science and Public Health Titles

Place: ABINGDON

Publication year: 2012

Journal: Natural Product Research (1478-6419)

Journal acronym: NAT PROD RES

Volume number: 26

Issue number: 19

Start page: 1817

End page: 1823

Number of pages: 7

ISSN: 1478-6419

eISSN: 1478-6427

Languages: English-Great Britain (EN-GB)

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Abstract

In this study, 12 compounds, which include a new flavanone 5-methoxy mundulin (1), were isolated from the leaves, stem bark and twigs of Mundulea sericea (Willd.) A. Chev. (Fabaceae; Papilionoideae). The structures of the compounds were identified based on spectral data analyses. The constituents of M. sericea also showed antimicrobial activities (MIQ = 0.01-100 mu g) against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans.

Keywords

5-methoxymundulin, antimicrobial, Fabaceae, flavanone, Mundulea sericea

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