SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF CYCLODIMERS OF STYRENE OXIDES

Journal article

Authors/Editors

Mazimba, Ofentse

Research Areas

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Publication Details

Author list: Mazimba O, Majinda RR, Masesane IB

Publisher: Chemical Society of Ethiopia

Place: ADDIS ABABA

Publication year: 2011

Journal acronym: B CHEM SOC ETHIOPIA

Volume number: 25

Issue number: 2

Start page: 299

End page: 304

Number of pages: 6

ISSN: 1011-3924

Languages: English-Great Britain (EN-GB)

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Abstract

A simple synthetic procedure for preparation of 1,4-dioxanes or 1,3-dioxolanes from styrene oxides is described. Electron-donating groups on the aromatic ring of the styrene oxides were found to favour formation of 1,4-dioxanes while electron-withdrawing groups favoured formation of 1,3-dioxolanes. Antibacterial activities of the prepared cyclodimers are reported.

Keywords

Antibacterial activities, Cyclodimerization, Dioxanes, Dioxolanes, Epoxidation, Styrene

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